Professor
Pediatric Surgery
Eiso Hiyama, MD, Ph.D.
Medical School
1982 Hiroshima University School of Medicine Hiroshima, M.D. 1989 Hiroshima University, Hiroshima, Ph.D.
Residency
1983 Junior Resident in the First Department of Surgery, Hiroshima University Medical Hospital
Fellowship
1994 Assistant Professor in Department of General Medicine, Hiroshima University Medical Hospital
2001 Associate Professor in Department of General Medicine, Hiroshima University Medical Hospital
2004 Professor, Natural Science of Basic Research and Development, Graduate School of Biomedical Sciences, Hiroshima University & epartment of Pediatric Surgery, Hiroshima University Hospital, Hiroshima, Japan
2007 Director, Division of Life Science, Natural Science of Basic Research and Development, Hiroshima University
Speciality
Research interest
1) Pediatric Oncology (Solid tumor)
2) Clinical genetics & Cancer
3) Molecular medicine
4) Surgical Infection
5) Pediatric surgery
6) Regenerative Medicine
Certification
Examination of National Medical Board 1982
Board Certified Surgeon 1999
Board Certified Pediatric Surgeon 2001
Board Certified Clinical Genetics 2003
Board Certified Cancer Therapy 2008
Academic Rank
Medical Doctor
Publications
Hiyama E, Iehara T, Sugimoto T, Fukuzawa M, Hayashi Y, Sasaki F, Sugiyama M, Kondo S, Yoneda A, Yamaoka H, Tajiri T, Akazawa K, Ohtaki M. Effectiveness of screening for neuroblastoma at 6 months of age: a retrospective population-based cohort study.
Lancet. 2008 Apr 5;371(9619):1173-80.
Hiyama E, Yamaoka H, Kondo S, Yoneda A, Tajiri T, Fukuzawa M, Sugiyama M, Hayashi Y, Sasaki F, Ohtaki M. Heterogeneous subgroups in human neuroblastoma for clinically relevant risk stratification.
Pediatr Surg Int. 2007 Nov;23(11):1051-8. Epub 2007 Aug 16.
Hiyama E, Hiyama K. Telomere and telomerase in stem cells.
Br J Cancer. 2007 Apr 10;96(7):1020-4. Epub 2007 Mar 13. Review.
Hiyama E, Yamaoka H, Kamimatsuse A, Onitake Y, Hiyama K, Nishiyama M, Sueda T. Single nucleotide polymorphism array analysis to predict clinical outcome in neuroblastoma patients.
J Pediatr Surg. 2006 Dec;41(12):2032-6.
Hiyama E, Hiyama K, Yamaoka H, Sueda T, Reynolds CP, Yokoyama T.
Expression profiling of favorable and unfavorable neuroblastomas.
Pediatr Surg Int. 2004 Jan;20(1):33-8. Epub 2003 Dec 23.
Hiyama E, Hiyama K, Nishiyama M, Reynolds CP, Shay JW, Yokoyama T.
Differential gene expression profiles between neuroblastomas with high telomerase activity and low telomerase activity.
J Pediatr Surg. 2003 Dec;38(12):1730-4.
Hiyama E, Hiyama K. Telomerase as tumor marker.
Cancer Lett. 2003 May 15;194(2):221-33. Review.
Hiyama E, Hiyama K. Clinical utility of telomerase in cancer.
Oncogene. 2002 Jan 21;21(4):643-9. Review.
Hiyama E, Kodama T, Shinbara K, Iwao T, Itoh M, Hiyama K, Shay JW, Matsuura Y, Yokoyama T. Telomerase activity is detected in pancreatic cancer but not in benign tumors.
Cancer Res. 1997 Jan 15;57(2):326-31.
Hiyama E, Hiyama K, Ohtsu K, Yamaoka H, Ichikawa T, Shay JW, Yokoyama T. Telomerase activity in neuroblastoma:is it a prognostic indicator of clinical behavior.
Eur J Cancer. 1997 Oct;33(12):1932-6
Hiyama E, Hiyama K, Yokoyama T, Matsuura Y, Piatyszek MA, Shay JW. Correlating telomerase activity levels with human neuroblastoma outcomes.
Nature Med 1995;1:249-255.
Hiyama E, Yokohama T, Hiyama K, Yamakido M, Santo T, Kodama T, Ichikawa T, Matsuura Y. Alteration of telomeric repeat length in adult and childhood solid neoplasias.
Int J Oncol. 1995 Jan;6(1):13-6.
Hiyama E, Yokoyama T, Ichikawa T, Hiyama K, Kobayashi M, Tanaka Y, Ueda K, Tanaka Y, Yano H. Poor outcome in patients with advanced stage neuroblastoma and concident opsomyoclonus syndrome.
Cancer. 1994;15;74(6):1821-6.
Hiyama E, Yokoyama T, Ichikawa T, Matsuura Y. Surgical management of tracheal agenesis.
J Thorac Cardiovasc Surg. 1994 Nov;108(5):830-3.
Hiyama E, Yokoyama T, Tatsumoto N, Hiyama K, Imamura Y, Murakami Y, Kodama T, Piatyszek MA, Shay JW, Matsuura Y. Telomerase activity in gastric cancer.
Cancer Res. 1995 Aug 1;55(15):3258-62.
Hiyama E, Hiyama K, Yokoyama T. Neuroblastoma with DNA amplification and rearrangement in the N-myc gene regition.
Cancer Res. 1991 Apr 1;51(7):1946-51.
et al. (total 165)
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