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  4. EisoHiyama

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 Hiyama_E.jpg Hiyama_E.jpg 

Hiyama_E.jpg 

 Faculty members

 

Professor

Pediatric Surgery  

Assistant ProfessorHBP surgery  Eiso Hiyama, MD,  PhD

 

Medical School

 

1982  Hiroshima University School of Medicine Hiroshima, M.D.                   1989 Hiroshima University, Hiroshima, Ph.D. 

   

Residency  

 

1983  Junior Resident in the First Department of Surgery, Hiroshima University Medical Hospital   

 

 

Fellowship

 

1994 Assistant Professor in Department of General Medicine, Hiroshima University Medical Hospital 

2001 Associate Professor in Department of General Medicine, Hiroshima University Medical Hospital 

2004   Professor, Natural Science of Basic Research and Development, Graduate School of Biomedical Sciences, Hiroshima University & epartment of Pediatric Surgery, Hiroshima University Hospital, Hiroshima, Japan 

2007   Director, Division of Life Science, Natural Science of Basic Research and Development, Hiroshima University 

 

Speciality

 

 

 

Research interest

 

1) Pediatric Oncology (Solid tumor)

2) Clinical genetics & Cancer

3) Molecular medicine

4) Surgical Infection

5) Pediatric surgery

6) Regenerative Medicine  

  

Certification

 

Examination of National Medical Board                      1982   

Board Certified Surgeon                                1999

Board Certified Pediatric Surgeon                  2001   

Board Certified Clinical Genetics                    2003

Board Certified Cancer Therapy                             2008 

 

Academic Rank

 

Medical Doctor  

 

Publications

 

Hiyama E, Iehara T, Sugimoto T, Fukuzawa M, Hayashi Y, Sasaki F, Sugiyama M, Kondo S, Yoneda A, Yamaoka H, Tajiri T, Akazawa K, Ohtaki M. Effectiveness of screening for neuroblastoma at 6 months of age: a retrospective population-based cohort study. Pubmed_index.jpg

Lancet. 2008 Apr 5;371(9619):1173-80.

 

Hiyama E, Yamaoka H, Kondo S, Yoneda A, Tajiri T, Fukuzawa M, Sugiyama M, Hayashi Y, Sasaki F, Ohtaki M. Heterogeneous subgroups in human neuroblastoma for clinically relevant risk stratification. Pubmed_index.jpg

Pediatr Surg Int. 2007 Nov;23(11):1051-8. Epub 2007 Aug 16.

 

Hiyama E, Hiyama K. Telomere and telomerase in stem cells. Pubmed_index.jpg

Br J Cancer. 2007 Apr 10;96(7):1020-4. Epub 2007 Mar 13. Review.

 

Hiyama E, Yamaoka H, Kamimatsuse A, Onitake Y, Hiyama K, Nishiyama M, Sueda T. Single nucleotide polymorphism array analysis to predict clinical outcome in neuroblastoma patients. Pubmed_index.jpg

J Pediatr Surg. 2006 Dec;41(12):2032-6.

 

Hiyama E, Hiyama K, Yamaoka H, Sueda T, Reynolds CP, Yokoyama T.

Expression profiling of favorable and unfavorable neuroblastomas. Pubmed_index.jpg

Pediatr Surg Int. 2004 Jan;20(1):33-8. Epub 2003 Dec 23.

 

Hiyama E, Hiyama K, Nishiyama M, Reynolds CP, Shay JW, Yokoyama T.

Differential gene expression profiles between neuroblastomas with high telomerase activity and low telomerase activity. Pubmed_index.jpg

J Pediatr Surg. 2003 Dec;38(12):1730-4.

 

Hiyama E, Hiyama K. Telomerase as tumor marker. Pubmed_index.jpg

Cancer Lett. 2003 May 15;194(2):221-33. Review.

 

Hiyama E, Hiyama K. Clinical utility of telomerase in cancer. Pubmed_index.jpg

Oncogene. 2002 Jan 21;21(4):643-9. Review.

 

Hiyama E, Kodama T, Shinbara K, Iwao T, Itoh M, Hiyama K, Shay JW, Matsuura Y, Yokoyama T. Telomerase activity is detected in pancreatic cancer but not in benign tumors. Pubmed_index.jpg

Cancer Res. 1997 Jan 15;57(2):326-31.


Hiyama E, Hiyama K, Ohtsu K, Yamaoka H, Ichikawa T, Shay JW, Yokoyama T. Telomerase activity in neuroblastoma:is it a prognostic indicator of clinical behavior. Pubmed_index.jpg

Eur J Cancer. 1997 Oct;33(12):1932-6

 

Hiyama E, Hiyama K, Yokoyama T, Matsuura Y, Piatyszek MA, Shay JW. Correlating telomerase activity levels with human neuroblastoma outcomes. Pubmed_index.jpg

Nature Med 1995;1:249-255.

 

Hiyama E, Yokohama T, Hiyama K, Yamakido M, Santo T, Kodama T, Ichikawa T, Matsuura Y. Alteration of telomeric repeat length in adult and childhood solid neoplasias. Pubmed_index.jpg

Int J Oncol. 1995 Jan;6(1):13-6.

 

Hiyama E, Yokoyama T, Ichikawa T, Hiyama K, Kobayashi M, Tanaka Y, Ueda K, Tanaka Y, Yano H. Poor outcome in patients with advanced stage neuroblastoma and concident opsomyoclonus syndrome. Pubmed_index.jpg

Cancer. 1994;15;74(6):1821-6.


Hiyama E, Yokoyama T, Ichikawa T, Matsuura Y. Surgical management of tracheal agenesis. Pubmed_index.jpg

J Thorac Cardiovasc Surg. 1994 Nov;108(5):830-3.

 

Hiyama E, Yokoyama T, Tatsumoto N, Hiyama K, Imamura Y, Murakami Y, Kodama T, Piatyszek MA, Shay JW, Matsuura Y. Telomerase activity in gastric cancer. Pubmed_index.jpg

Cancer Res. 1995 Aug 1;55(15):3258-62.


Hiyama E, Hiyama K, Yokoyama T. Neuroblastoma with DNA amplification and rearrangement in the N-myc gene regition.Pubmed_index.jpg

Cancer Res. 1991 Apr 1;51(7):1946-51.

 

et al. (total 165)

 

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